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Weichselbaum, Ralph R.
One or more keywords matched the following items that are connected to Weichselbaum, Ralph R.
Item TypeName
Concept Cell Line, Transformed
Concept Cell Line, Tumor
Concept Cell Line
Academic Article C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure.
Academic Article Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation.
Academic Article The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Academic Article Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Academic Article Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.
Academic Article Differential retention of tumor- and differentiation-suppressor functions in cells derived from a human squamous cell carcinoma.
Academic Article The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines.
Academic Article Functional interaction between DNA-PK and c-Abl in response to DNA damage.
Academic Article The contribution of DNA ploidy to radiation sensitivity in human tumour cell lines.
Academic Article In vivo replication-deficient adenovirus vector-mediated transduction of the cytosine deaminase gene sensitizes glioma cells to 5-fluorocytosine.
Academic Article Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase.
Academic Article Regulation of Rad51 function by c-Abl in response to DNA damage.
Academic Article p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
Academic Article Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Academic Article Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.
Academic Article Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage.
Academic Article Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
Academic Article Anti-angiogenic cues from vascular basement membrane collagen.
Academic Article E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
Academic Article Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3.
Academic Article cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.
Academic Article Radiation-induced DNA double-strand break frequencies in human squamous cell carcinoma cell lines of different radiation sensitivities.
Academic Article cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
Academic Article Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process.
Academic Article Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
Academic Article Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.
Academic Article Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.
Academic Article Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize.
Academic Article Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance.
Academic Article Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
Academic Article Two prostate carcinoma cell lines demonstrate abnormalities in tumor suppressor genes.
Academic Article Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance.
Academic Article Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
Academic Article Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
Academic Article Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells.
Academic Article Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
Academic Article Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
Academic Article Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.
Academic Article Ionizing radiation regulates expression of the c-jun protooncogene.
Academic Article Symmetrical chromosome rearrangements in cell lines established from human radiation-induced sarcomas.
Academic Article An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
Academic Article Tumor genotype determines susceptibility to oncolytic herpes simplex virus mutants: strategies for clinical application.
Academic Article Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution.
Academic Article Variation in radiation sensitivity during the cell cycle of two human squamous cell carcinomas.
Academic Article Response of human osteosarcoma in vitro to irradiation: evidence for unusual cellular repair activity.
Academic Article Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts.
Academic Article Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.
Academic Article Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
Academic Article Characterization of response to radiation mediated gene therapy by means of multimodality imaging.
Academic Article MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients.
Academic Article Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.
Academic Article Radiobiological characterization of 53 human tumor cell lines.
Academic Article STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.
Academic Article Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors.
Academic Article Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.
Academic Article Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
Academic Article Platinum complexes inhibit repair of potentially lethal damage following bleomycin treatment.
Academic Article Sensitivities of NIH/3T3-derived clonal cell lines to ionizing radiation: significance for gene transfer studies.
Academic Article Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
Academic Article Radioresistant tumor cell lines derived from head and neck radiation failures.
Academic Article Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines.
Academic Article Heterogeneity of radiation response of a parent human epidermoid carcinoma cell line and four clones.
Academic Article Similar sensitivity of human lymphoblast cells proficient or deficient in nucleotide biosynthesis to the cytotoxic and cell cycle effects of 3-aminobenzamide.
Academic Article SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine.
Academic Article Faster repair of DNA double-strand breaks in radioresistant human tumor cells.
Academic Article Proliferation kinetics of a human breast cancer line in vitro following treatment with 17beta-estradiol and 1-beta-D-arabinofuranosylcytosine.
Academic Article The mechanism of 3-aminobenzamide-mediated increases in spontaneous and induced SCEs.
Academic Article Cellular X-ray repair parameters of early passage squamous cell carcinoma lines derived from patients with known responses to radiotherapy.
Academic Article Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells.
Academic Article An epidermoid carcinoma cell line derived from hamster 7,12-dimethylbenz[a]anthracene-induced buccal pouch tumors.
Academic Article Response of human fibroblasts to low dose rate gamma irradiation.
Academic Article Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients.
Academic Article The maximum recovery potential of human tumor cells may predict clinical outcome in radiotherapy.
Academic Article Repair of potentially lethal X ray damage and possible applications to clinical radiotherapy.
Academic Article Cellular repair factors influencing radiocurability of human malignant tumours.
Academic Article Repair of potentially lethal X-ray damage in fibroblasts derived from patients with hereditary and D-deletion retinoblastoma.
Academic Article Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.
Academic Article Overexpression of Bcl-XL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation.
Academic Article X-ray and cis-diamminedichloroplatinum(II) cross-resistance in human tumor cell lines.
Academic Article Radioresistant and repair proficient cells may determine radiocurability in human tumors.
Academic Article Recovery from sublethal and potentially lethal damage in an X-ray-sensitive CHO cell.
Academic Article The role of DNA repair processes in the response of human tumors to fractionated radiotherapy.
Academic Article Quantitation of the response of human tumor spheroids to daily radiation exposures.
Academic Article Protease inhibitor antipain reduces nuclear binding of estrogen-receptor complex in MCF-7 breast tumor cells.
Academic Article In vitro radiosensitivity of human leukemia cell lines.
Academic Article Effects of 17 beta-estradiol on radiation transformation in vitro; inhibition of effects by protease inhibitors.
Academic Article X-ray sensitivity of human tumor cells in vitro.
Academic Article Lack of selective killing by steroids in normal and malignant cells.
Academic Article Modification by dexamethasone of radiation response of in vitro cultured cells.
Academic Article Effects of estradiol concentration on levels of nuclear estrogen receptors in MCF-7 breast tumor cells.
Academic Article Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Academic Article In vitro radiobiological parameters of human sarcoma cell lines.
Academic Article Combination hormonal, chemotherapy and radiotherapy in vitro: implications for therapy in vivo.
Academic Article A technique for developing established cell lines from human osteosarcomas.
Academic Article The raf oncogene is associated with a radiation-resistant human laryngeal cancer.
Academic Article Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
Academic Article Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
Academic Article Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy.
Academic Article Iodine-125-labelled tamoxifen is differentially cytoxic to cells containing oestrogen receptors.
Academic Article Fraction size and the repair of potentially lethal radiation damage in a human melanoma cell line. Possible implications for radiotherapy.
Academic Article Radioresistance in some human tumor cells conferred in vitro by repair of potentially lethal X-ray damage.
Academic Article Growth and magnetic resonance characteristics of human squamous cell carcinoma xenografts implanted with cells suspended in Matrigel.
Academic Article Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
Academic Article Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
Academic Article Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
Academic Article DNA repair in a Fanconi's anemia fibroblast cell strain.
Academic Article Inherently radioresistant cells exist in some human tumors.
Academic Article Differing patterns of cytotoxicity of the phorbol ester 12-O-tetradecanoylphorbol 13-acetate in various human cell strains.
Academic Article Effects of serum-free defined medium on MCF-7 cell nuclear estrogen-receptor levels.
Academic Article Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms.
Academic Article New findings in the chromosome 13 long-arm deletion syndrome and retinoblastoma.
Academic Article Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis.
Academic Article Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326.
Academic Article In vitro cellular radiosensitivity of human malignant tumors.
Academic Article Measurement of bioreduction rates of cells with distinct responses to ionizing radiation and cisplatin.
Academic Article Radioresistant derivatives of an X-ray-sensitive CHO cell line exhibit distinct patterns of sensitivity to DNA-damaging agents.
Academic Article Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.
Academic Article Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.
Academic Article Monosomy 12p in a radiation-induced germ cell tumor.
Academic Article Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
Academic Article The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
Academic Article Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis.
Academic Article Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
Academic Article p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage.
Academic Article MicroRNA expression characterizes oligometastasis(es).
Academic Article Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.
Academic Article Expression and methylation of the Blym gene in human tumor cell lines.
Academic Article Work in progress: radioprotection of human breast cancer cells by elevation of intracellular cyclic AMP.
Academic Article Potentially lethal damage repair as a possible determinant of human tumour radiosensitivity.
Academic Article The repair of potentially lethal damage in x-irradiated cultures of normal and ataxia telangiectasia human fibroblasts.
Academic Article The differential response of human tumours to fractionated radiation may be due to a post-irradiation repair process.
Academic Article Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation.
Academic Article p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Academic Article Estrogen receptor-mediated cytotoxicity using iodine-125.
Academic Article Release of spleen focus-forming virus (SFFV) from differentiation inducible promyelocytic leukemia cell lines transformed in vitro by Friend leukemia virus.
Academic Article DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.
Academic Article A manganese superoxide dismutase (SOD2)-mediated adaptive response.
Academic Article A survivin-associated adaptive response in radiation therapy.
Academic Article Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK.
Academic Article Targeting the tumor microenvironment with interferon-ß bridges innate and adaptive immune responses.
Academic Article Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer.
Academic Article Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma.
Academic Article RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.
Academic Article Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.
Academic Article The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors.
Academic Article DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.
Academic Article Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
Academic Article 14q32-encoded microRNAs mediate an oligometastatic phenotype.
Academic Article Imaging of tumor clones with differential liver colonization.
Academic Article Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome.
Academic Article MUC1-C activates the TAK1 inflammatory pathway in colon cancer.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Tumor-associated fibroblasts predominantly come from local and not circulating precursors.
Academic Article Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy.
Academic Article Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.
Academic Article Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity.
Academic Article Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance.
Academic Article Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer.
Academic Article Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication.
Academic Article CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.
Academic Article Tumour ischaemia by interferon-? resembles physiological blood vessel regression.
Academic Article Host STING-dependent MDSC mobilization drives extrinsic radiation resistance.
Academic Article BCL3 expression promotes resistance to alkylating chemotherapy in gliomas.
Academic Article Oxygen-Guided Radiation Therapy.
Academic Article Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy.
Academic Article Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma.
Academic Article Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors.
Academic Article Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy.
Academic Article Tumor-reprogrammed resident T cells resist radiation to control tumors.
Academic Article Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling.
Academic Article p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.
Academic Article RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy.
Academic Article The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes.
Academic Article CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma.
Academic Article Sunitinib-Loaded Chondroitin Sulfate Hydrogels as a Novel Drug-Delivery Mechanism for the Treatment of Pancreatic Neuroendocrine Tumors.
Academic Article The relationship between expression of PD-L1 and HIF-1a in glioma cells under hypoxia.
Academic Article All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages.
Academic Article Tumor-Activatable Nanoparticles Target Low-Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy.
Academic Article Nanoscale Metal-Organic Framework with an X-ray Triggerable Prodrug for Synergistic Radiotherapy and Chemotherapy.
Academic Article Nanoscale Covalent Organic Framework with Staggered Stacking of Phthalocyanines for Mitochondria-Targeted Photodynamic Therapy.
Academic Article Immunogenic Bifunctional Nanoparticle Suppresses Programmed Cell Death-Ligand 1 in Cancer and Dendritic Cells to Enhance Adaptive Immunity and Chemo-Immunotherapy.
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